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经验分子式（希尔表示法） C16H10O7
分子量 314.25
MDL number MFCD07778564
PubChem Substance ID 24724667
Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα. Irreversible inhibitor of IKKα and β kinase activity (IC50 < 10 μM). Wedelolactone has no effects on p38 MAP kinase or Akt.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. W4016.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to brown |
| solubility | DMSO: soluble10 mg/mL, clear |
| storage temp. | 2-8°C |
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