经验分子式(希尔表示法) C16H16ClN5O3
分子量 361.78
This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
Sold for research purposes under agreement from Pfizer Inc.
PF-04802367 (PF-367) is a potent and specific ATP-competitive inhibitor of glycogen synthase kinase 3 (GSK-3α/β) with an IC50 value of 2.3 nM and >450-fold selectivity for GSK-3 in a panel of >400 neuroreceptors, enzymes and kinases. GSK-3 dysregulation has been implicated in the pathogenesis of neurological diseases including Alzheimer′s disease.
assay | ≥98% (HPLC) |
form | powder |
color | white to beige |
solubility | DMSO: soluble20 mg/mL, clear |
shipped in | wet ice |
storage temp. | ?20°C |
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