经验分子式(希尔表示法) C17H15NO3
分子量 281.31
MDL number MFCD06798345
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Potent, ATP-competitive. IC50 = 0.23 μM. Selectivity over other PI3K-related kinases (IC50 = 13 μM for PI3K and >100 μM for ATM and ATR).
Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).
5 mg in glass bottle
assay | ≥98% (HPLC) |
form | solid |
color | tan |
solubility | DMSO: soluble3 mg/mL at 60 °C |
H2O: insoluble | |
shipped in | wet ice |
storage temp. | 2-8°C |
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