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PHA 767491 hydrochloride ≥98% (HPLC)

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号:PZ0178-25MG

牌:Sigma 西格玛

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别名: 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride PHA-00767491 hydrochloride
  • 经验分子式(希尔表示法) C12H11N3O · xHCl

  • 分子量 213.24 (free base basis)

  •  MDL number MFCD11519962

产品名称

Other Notes

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

法律信息

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Biochem/physiol Actions

PHA-767491 is a potent and selective ATP-competitive dual inhibitor cdc7/cdk9. PHA-767491 blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.


性质

assay   ≥98% (HPLC)
form   powder
color   off-white to yellow
solubility   H2O: >25 mg/mL
originator   Pfizer

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