经验分子式(希尔表示法) C16H11N3O3
分子量 293.28
MDL number MFCD02683579
PubChem Substance ID 24890918
Potent and selective inhibitor of GSK-3β and CDK5/p25; potent inhibitor of CDK1/cyclin B (IC50 = 0.035 μM).
Alsterpaullone inhibits GSK-3β, CDK5/p25, and CDK1/cyclin B. Alsterpaullone has also been studied as an antimanic therapeutic for the acute manic phase of bipolar disorder.
This compound is featured on the CDKs and GSK-3 pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
assay | ≥98% (HPLC) |
form | powder |
storage condition | desiccated |
color | yellow to brown |
solubility | DMSO: ≥10 mg/mL |
storage temp. | 2-8°C |
Gene Information | rat ... Gsk3b(84027) |
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