经验分子式(希尔表示法) C16H14BrN3O3
分子量 376.20
WHI-P154 is a specific inhibitor of JAK3 (IC50 = 1.8 μM) with no inhibitory activity against JAK1 or JAK2. WHI-P154 enhances myogenic differentiation of C2C12 mouse myoblast cells, and induces differentiation of neural progenitor cells. The compound WHI-P154 dose dependently inhibits expression of iNOS and NO production in LPS-challenged macrophages.
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assay | ≥98% (HPLC) |
form | powder |
color | white to brown |
solubility | DMSO: soluble1 mg/mL, clear (warmed) |
storage temp. | ?20°C |
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