PF-04965842 ≥98% (HPLC)

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PF-04965842 ≥98% (HPLC)

市场价：: 0.00

促销价：: ¥0.00

货号：PZ0304-5MG

品牌：Sigma 西格玛

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EA (预计5-7工作日到货(以Sigma 西格玛官网货期为准))

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商品介绍
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别名: N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}-propane-1-sulfonamide

经验分子式（希尔表示法） C₁₄H₂₁N₅O₂S
分子量 323.41

产品名称

Other Notes

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Biochem/physiol Actions

PF-04965842 is a Janus Kinase (JAK) inhibitor selective for JAK1 with an IC₅₀ value of 29 nM for JAK1 compared to 803 nM for JAK2, >10000 nM for JAK3 and 1250 nM for Tyk2. JAKs mediate cytokine signaling, and are involved in cell proliferation and differentiation. PF-04965842 has been investigated as a possible treatment for psoriasis.