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Cucurbitacin I Cucurbitacin I hydrate ≥95% (HPLC), solid

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号:C4493-1MG

牌:Sigma 西格玛

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别名: 2,16α,20,25-tetrahydroxy-9-methyl-19-Nor-9β,10α-lanosta-1,5,23-triene-3,11,22-trione Elatericin B JSI-124 NSC 521777
  • 经验分子式(希尔表示法) C30H42O7 · xH2O

  • 分子量 514.65 (anhydrous basis)

  •  EINECS 编号 218-736-8

产品名称

Biochem/physiol Actions

Cucurbitacin I (JSI-124) is a novel selective inhibitor of the janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signaling pathway with anti-proliferative and anti-tumor properties.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the JAKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


性质

assay   ≥95% (HPLC)
form   solid
color   white to off-white
solubility   DMSO: >5 mg/mL
storage temp.   ?20°C

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