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(±)-止呕灵 (±)-Sulpiride

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号:S8010-100G

牌:Sigma 西格玛

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别名: (±)-5-氨基磺酰基-N-[(1-乙基-2-吡咯烷基)甲基]-2-甲氧基苯甲酰胺 (±)-N-1-(乙基-2-吡咯基甲基)-2-甲氧基-5-氨磺酰苯甲酰胺
  • 经验分子式(希尔表示法) C15H23N3O4S

  • 分子量 341.43

  •  EINECS 编号 239-753-7

  •  MDL number MFCD00055061

  •  PubChem Substance ID 24277933

产品名称

Reconstitution

Solutions may be stored for several days at 4 °C.

Application

(±)-Sulpiride was used to study the effect of dopamine D2 receptor signaling on calcium channels in rat pituitary melanotropic cells.47

Biochem/physiol Actions

(±)-Sulpiride is a D2 dopamine antagonist and an effective treatment for schizophrenia when used in combination with clozapine, a relatively weak D2-dopaminergic antagonist. It is an antipsychotic agent and also exhibits neuroleptic properties but poorly penetrates the central nervous system.45,46

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC


性质

form   powder
color   white
solubility   45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble8.0 mg/mL
  0.1 M HCl: soluble
  H2O: slightly soluble
  ethanol: soluble
originator   Sanofi Aventis
storage temp.   2-8°C
Gene Information   human ... CA1(759), CA2(760), CA4(762), CA5A(763), CA5B(11238), CA9(768), DRD2(1813)

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