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经验分子式（希尔表示法） C21H22N4O6S · H2O
分子量 476.50
MDL number MFCD12828867
10 mg in glass bottle
50 mg in poly bottle
Raltitrexed is a folate-based inhibitor of thymidylate synthase (TS) that is rapidly and extensively metabolized to its more potent polyglutamate derivatives. By inhibiting the formation of precursor pyrimidine nucleotides, raltitrexed prevents the formation of DNA and RNA, which are required for the growth and survival of both normal cells and cancer cells.
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
| assay | ≥98% (HPLC) |
| form | solid |
| color | off-white to light yellow |
| solubility | H2O: ≥10 mg/mL |
| DMSO: ≥40 mg/mL | |
| originator | AstraZeneca |
| storage temp. | 2-8°C |
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