经验分子式(希尔表示法) C16H16ClN3O6S
分子量 413.83
ML291 specifically activates the apoptotic arm of the cellular unfolded protein response ( UPR) EC50 = 762 nM) with 105-fold selectivity over activation of the adaptive UPR pathway. ML291 induces apoptosis in wild-type mouse embryonic fibroblasts (MEFs), but not in CHOP KO MEFs.
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assay | ≥98% (HPLC) |
form | powder |
color | white to beige |
solubility | DMSO: soluble20 mg/mL, clear |
storage temp. | 2-8°C |
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