经验分子式(希尔表示法) C10H13N5O5 · xH2O
分子量 283.24 (anhydrous basis)
MDL number MFCD00065486
Ara-G is converted by cellular kinases to the active 5′-triphosphate, Ara-GTP. This active form of Ara-G induces apoptosis and inhibits DNA synthesis. Ara-G is also an antineoplastic and antimetabolite.
Ara-G is an inducer of apoptosis; inhibitor of DNA synthesis; antineoplastic; and antimetabolite. Ara-G is converted by cellular kinases to the active 5′-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis.
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assay | ≥98% (HPLC) |
form | solid |
solubility | DMSO: >10 mg/mL |
H2O: insoluble | |
storage temp. | 2-8°C |
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