经验分子式(希尔表示法) C20H28O2
分子量 300.44
Beilstein Registry Number 2057223
EINECS 编号 206-129-0
MDL number MFCD00001551
PubChem Substance ID 24278674
Popular Documents: Product Information Sheet (PDF) | Specification Sheet (PDF) | FTNMR (PDF)
Frequently Asked Questions are available for this Product.
1, 5 g in ampule
50, 100, 500 mg in ampule
all?trans?Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R2625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
assay | ≥98% (HPLC) |
form | powder |
color | yellow |
mp | 180-181 °C(lit.) |
storage temp. | ?20°C |
Gene Information | human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258) mouse ... Rara(19401), Rarb(218772), Rarg(19411), Rxrb(20182) |
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