别名: 5-
经验分子式(希尔表示法) C12H11NOS2
分子量 249.35
MDL number MFCD00758517
10058-F4 is a c-Myc inhibitor that induces cell-cycle arrest and apoptosis. 10058-F4 is a cell-permeable thiazolidinone that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression. 10058-F4 inhibits tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (64 μM using c-Myc transfected Rat1a fibroblasts).
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assay | ≥98% (HPLC) |
form | solid |
color | yellow |
solubility | DMSO: >10 mg/mL |
H2O: <2 mg/mL | |
storage temp. | 2-8°C |
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