生物活性 |
Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects[1]. |
||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IC50 & Target |
|
||||||||||||||||
体外研究 (In Vitro) |
Tyrosol (1.6 mM) significantly increases the cell viability of cultured astrocytes exposed to oxygen glucose deprivation (OGD)[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||
体内研究 (In Vivo) |
Sub-plantar injection of carrageenan causes a noticeable increase in paw thickness, reaching a peak after 2 h post-injection. This effect is reduced when Tyrosol (0.5 mg/kg) or Tyrosol-sulphate is injected prior to the treatment with carrageenan. Similar AUC values for paw oedema are obtained after the administration of Tyrosol at a dose of 0.5 mg/kg and Tyrosol-sulphate at a dose of 0.1 mg/kg. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||
Clinical Trial |
|
||||||||||||||||
分子量 |
138.16 |
||||||||||||||||
Formula |
C8H10O2 |
||||||||||||||||
CAS 号 | |||||||||||||||||
中文名称 |
酪醇 |
||||||||||||||||
结构分类 | |||||||||||||||||
来源 | |||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||
储存方式 |
4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : ≥ 100 mg/mL (723.80 mM) * "≥" means soluble, but saturation unknown.
配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 MCE 网站选购。
|
||||||||||||||||
纯度 & 产品资料 |
|
||||||||||||||||
参考文献 |
|
温馨提示:因厂家更改产品包装、产地或者更换随机附件等没有任何提前通知,且每位咨询者购买情况、提问时间等不同,为此以下回复仅对提问者3天内有效,其他网友仅供参考!若由此给您带来不便请多多谅解,谢谢!
服务热线
0771-3293894