Our Boronate Resin is designed for the isolation of ribonucleotide and oligonucleotide RNA.The resin consists of boronic acid covalently linked to a polyacrylamide support that offers simple isolation of small molecular weight compounds that have cis-diol groups. The immobilized boronic acid interacts with the cis-diol groups, found in the sugar portion of nucleotides, forming a reversible five member ring complex. Impurities are washed away and then the complex dissociated by low pH or presence of sorbitol.
The polyacrylamide support excludes >6000 Da molecules from entering the resin bed and therefore is suitable only for small molecules.
2 ml resin
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