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| Clone Name | OTI4C5 |
| Applications | FC, IF, WB |
| Recommend Dilution | WB 1:1000, IF 1:100, Flow 1:100 |
| Reactivity | Human, Mouse, Rat, Dog |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human HK2 (NP_000180) produced in HEK293T cell. |
| Isotype | IgG1 |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 102.4 kDa |
| Gene Name | hexokinase 2 |
| Database Link | |
| Background | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways.This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. |
| Synonyms | HKII; HXK2 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus |
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