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| Product Data | |
| Description | Purified recombinant protein of Human cereblon (CRBN), transcript variant 1, full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | A DNA sequence from TrueORF clone, RC209794, encoding the full-length of CRBN |
| Tag | Myc-DDK |
| Predicted MW | 50.5 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Reference Data | |
| Locus ID | 51185 |
| Refseq Size | 2596 |
| Cytogenetics | 3p26.2 |
| Refseq ORF | 1326 |
| Synonyms | MRT2; MRT2A |
| Summary | This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
| Protein Families | Protease |
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