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| Product Data | |
| Description | Purified recombinant protein of Human eomesodermin (EOMES), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | A DNA sequence from TrueORF clone, RC221014, encoding the full-length of EOMES |
| Tag | Myc-DDK |
| Predicted MW | 72.6 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Reference Data | |
| Locus ID | 8320 |
| Refseq Size | 2756 |
| Cytogenetics | 3p24.1 |
| Refseq ORF | 2058 |
| Synonyms | TBR2 |
| Summary | This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
| Protein Families | Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors |
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