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| Product Data | |
| Description | Recombinant protein of human death-associated protein kinase 1 (DAPK1) |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC215423. Click on the TrueORF clone link to view cDNA and protein sequences. |
| Tag | C-Myc/DDK |
| Predicted MW | 159.9 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Reference Data | |
| Locus ID | 1612 |
| Refseq Size | 5910 |
| Cytogenetics | 9q21.33 |
| Refseq ORF | 4290 |
| Synonyms | DAPK; ROCO3 |
| Summary | Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Bladder cancer, Pathways in cancer |
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