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| Product Data | |
| Description | Recombinant protein of human clathrin interactor 1 (CLINT1), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | A DNA sequence encoding human full-length CLINT1 |
| Tag | N-His |
| Predicted MW | 68.3 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg |
| Reference Data | |
| Locus ID | 9685 |
| Refseq Size | 4007 |
| Cytogenetics | 5q33.3 |
| Refseq ORF | 1875 |
| Synonyms | CLINT; ENTH; EPN4; EPNR |
| Summary | This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010] |
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