Product Data | |
Description | Recombinant protein of human ChaC, cation transport regulator homolog 2 (E. coli) (CHAC2) |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC205083. Click on the TrueORF clone link to view cDNA and protein sequences. |
Tag | C-Myc/DDK |
Predicted MW | 20.7 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Reference Data | |
Locus ID | 494143 |
Refseq Size | 1305 |
Cytogenetics | 2p16.2 |
Refseq ORF | 552 |
Synonyms | ChaC, cation transport regulator-like 2; ChaC, cation transport regulator homolog 2 (E. coli); GCG1 |
Summary | The protein encoded by this gene is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine. It is thought that this gene is upregulated in response to endoplasmic reticulum stress and that the glutathione depletion enhances apoptosis. [provided by RefSeq, Sep 2016] |
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