Product Data | |
Description | Recombinant protein of human rho/rac guanine nucleotide exchange factor (GEF) 2 (ARHGEF2) |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC204546. Click on the TrueORF clone link to view cDNA and protein sequences. |
Tag | C-Myc/DDK |
Predicted MW | 108.1 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Reference Data | |
Locus ID | 9181 |
Refseq Size | 4119 |
Cytogenetics | 1q22 |
Refseq ORF | 2877 |
Synonyms | GEF; GEF-H1; GEFH1; LFP40; NEDMHM; P40 |
Summary | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2009] |
Protein Families | Druggable Genome |
Protein Pathways | Pathogenic Escherichia coli infection |
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