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| Product Data | |
| Description | Recombinant protein of human retinol dehydrogenase 10 (all-trans) (RDH10) |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC208980. Click on the TrueORF clone link to view cDNA and protein sequences. |
| Tag | C-Myc/DDK |
| Predicted MW | 37.9 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Reference Data | |
| Locus ID | 157506 |
| Refseq Size | 3981 |
| Cytogenetics | 8q21.11 |
| Refseq ORF | 1023 |
| Synonyms | SDR16C4 |
| Summary | This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011] |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Metabolic pathways, Retinol metabolism |
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