Product Data | |
Description | Recombinant protein of human enhancer of zeste homolog 1 (Drosophila) (EZH1) |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC202367. Click on the TrueORF clone link to view cDNA and protein sequences. |
Tag | C-Myc/DDK |
Predicted MW | 85.1 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Reference Data | |
Locus ID | 2145 |
Refseq Size | 4640 |
Cytogenetics | 17q21.2 |
Refseq ORF | 2241 |
Synonyms | KMT6B |
Summary | EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]). [supplied by OMIM, Mar 2009] |
Protein Families | Druggable Genome, Transcription Factors |
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