Product Data | |
Description | Recombinant protein of human ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 (ASAP3), transcript variant 1 |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC209195. Click on the TrueORF clone link to view cDNA and protein sequences. |
Tag | C-Myc/DDK |
Predicted MW | 99 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Reference Data | |
Locus ID | 55616 |
Refseq Size | 4199 |
Cytogenetics | 1p36.12 |
Refseq ORF | 2709 |
Synonyms | ACAP4; CENTB6; DDEFL1; UPLC1 |
Summary | This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
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