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| Product Data | |
| Description | Recombinant protein of human SH3-domain kinase binding protein 1 (SH3KBP1), transcript variant 1 |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC202186. Click on the TrueORF clone link to view cDNA and protein sequences. |
| Tag | C-Myc/DDK |
| Predicted MW | 72.9 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Reference Data | |
| Locus ID | 30011 |
| Refseq Size | 3348 |
| Cytogenetics | Xp22.12 |
| Refseq ORF | 1995 |
| Synonyms | AGMX2; CD2BP3; CIN85; GIG10; HSB-1; HSB1; IMD61; MIG18 |
| Summary | This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017] |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis |
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