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| Product Data | |
| Description | Recombinant protein of human neurolysin (metallopeptidase M3 family) (NLN) |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC212447. Click on the TrueORF clone link to view cDNA and protein sequences. |
| Tag | C-Myc/DDK |
| Predicted MW | 80.5 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Reference Data | |
| Locus ID | 57486 |
| Refseq Size | 2882 |
| Cytogenetics | 5q12.3 |
| Refseq ORF | 2112 |
| Synonyms | AGTBP; EP24.16; MEP; MOP |
| Summary | This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract. [provided by RefSeq, Jun 2010] |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Renin-angiotensin system |
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