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| Product Data | |
| Description | Recombinant protein of human serpin peptidase inhibitor, clade B (ovalbumin), member 4 (SERPINB4) |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC205612. Click on the TrueORF clone link to view cDNA and protein sequences. |
| Tag | C-Myc/DDK |
| Predicted MW | 44.7 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Reference Data | |
| Locus ID | 6318 |
| Refseq Size | 1787 |
| Cytogenetics | 18q21.33 |
| Refseq ORF | 1170 |
| Synonyms | LEUPIN; PI11; SCCA-2; SCCA1; SCCA2 |
| Summary | The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. [provided by RefSeq, Jan 2017] |
| Protein Families | Druggable Genome, Secreted Protein |
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