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| Product Data | |
| Product Name | glutathione S transferase Omega 1 (GSTO1) (NM_004832) Human Tagged ORF Clone |
| Symbol | GSTO1 |
| Synonyms | GSTO 1-1; GSTTLp28; HEL-S-21; P28; SPG-R |
| Vector | pCMV6-Entry |
| Sequence Data | >RC200362 ORF sequence Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCC GCGATCGC C ATGTCCGGGGAGTCAGCCAGGAGCTTGGGGAAGGGAAGCGCGCCCCCGGGGCCGGTCCCGGAGGGCTCGA TCCGCATCTACAGCATGAGGTTCTGCCCGTTTGCTGAGAGGACGCGTCTAGTCCTGAAGGCCAAGGGAAT CAGGCATGAAGTCATCAATATCAACCTGAAAAATAAGCCTGAGTGGTTCTTTAAGAAAAATCCCTTTGGT CTGGTGCCAGTTCTGGAAAACAGTCAGGGTCAGCTGATCTACGAGTCTGCCATCACCTGTGAGTACCTGG ATGAAGCATACCCAGGGAAGAAGCTGTTGCCGGATGACCCCTATGAGAAAGCTTGCCAGAAGATGATCTT AGAGTTGTTTTCTAAGGTGCCATCCTTGGTAGGAAGCTTTATTAGAAGCCAAAATAAAGAAGACTATGCT GGCCTAAAAGAAGAATTTCGTAAAGAATTTACCAAGCTAGAGGAGGTTCTGACTAATAAGAAGACGACCT TCTTTGGTGGCAATTCTATCTCTATGATTGATTACCTCATCTGGCCCTGGTTTGAACGGCTGGAAGCAAT GAAGTTAAATGAGTGTGTAGACCACACTCCAAAACTGAAACTGTGGATGGCAGCCATGAAGGAAGATCCC ACAGTCTCAGCCCTGCTTACTAGTGAGAAAGACTGGCAAGGTTTCCTAGAGCTCTACTTACAGAACAGCC CTGAGGCCTGTGACTATGGGCTC AG CGGACCG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA >RC200362 protein sequence Red=Cloning site Green=Tags(s) MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG LVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYA GLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDP TVSALLTSEKDWQGFLELYLQNSPEACDYGL SGPTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms | CHROMATOGRAMS  Sequencher program is needed, download here. |
| Restriction Sites | SgfI-RsrII Cloning Scheme for this gene Plasmid Map  |
| Tag | Myc-DDK |
| ACCN | NM_004832 |
| ORF Size | 723 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_004832.1, NM_004832.2, NP_004823.1 |
| RefSeq Size | 1017 bp |
| RefSeq ORF | 726 bp |
| Locus ID | 9446 |
| Cytogenetics | 10q25.1 |
| Domains | GST_N, GST_C |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450 |
| MW | 27.6 kDa |
| Gene Summary | The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
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