产品名称 | Recombinant Human Flt3-Ligand Protein |
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产品描述 | Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues. |
文献引用格式 | Recombinant Human Flt3-Ligand Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP49771-5) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Solid; white powder or thin/invisible film |
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内容 | Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | FLT3LG |
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基因全名 | Fms-related tyrosine kinase 3 ligand |
蛋白功能 | Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. |
Uniprot ID | FLT3LG: P49771 |
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