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| 产品名称 | Recombinant Human BMP-3 Protein |
|---|---|
| 产品描述 | TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-3 is abundantly found in adult bone, and to a lesser extent fetal cartilage. BMP-3 inhibits osteogenesis and bone formation by activating a signaling cascade that antagonizes the signaling of pro-osteogenic BMPs. Recombinant human BMP-3 is a disulfide linked homodimeric protein that corresponds to residues 361 to 472 of the 472 amino acid BMP-3 precursor protein. |
| 文献引用格式 | Recombinant Human BMP-3 Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP12645-1) |
| 应用范围 | Cell Culture |
| 抗体来源 | No |
| 产品形态 | Solid; white powder or thin/invisible film |
|---|---|
| 内容 | Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel. *可以提供无载体抗体。 |
| 储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
| 基因名 | BMP3 |
|---|---|
| 基因全名 | Bone morphogenetic protein 3 |
| 蛋白功能 | Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. . |
| Tissue Specificity | Expressed in adult and fetal cartilage. . |
| Uniprot ID | BMP3: P12645 |
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