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| 产品名称 | Recombinant Human BCMA Protein |
|---|---|
| 产品描述 | BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid cytoplasmic domain. Recombinant soluble BCMA is a 50 amino acid polypeptide (5.3 kDa) comprising the TNFR homologous region of the BCMA protein. |
| 文献引用格式 | Recombinant Human BCMA Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ02223) |
| 应用范围 | Cell Culture |
| 抗体来源 | No |
| 产品形态 | Solid; white powder or thin/invisible film |
|---|---|
| 内容 | Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel. *可以提供无载体抗体。 |
| 储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
| 基因名 | TNFRSF17 |
|---|---|
| 基因全名 | Tumor necrosis factor receptor superfamily member 17 |
| 蛋白功能 | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. . |
| Tissue Specificity | Expressed in mature B-cells, but not in T- cells or monocytes. |
| Uniprot ID | TNFRSF17: Q02223 |
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