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| 产品名称 | Recombinant Human 4-1BB Receptor Protein |
|---|---|
| 产品描述 | 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor. |
| 文献引用格式 | Recombinant Human 4-1BB Receptor Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ07011-4) |
| 应用范围 | Cell Culture |
| 抗体来源 | No |
| 产品形态 | Solid; white powder or thin/invisible film |
|---|---|
| 内容 | Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel. *可以提供无载体抗体。 |
| 储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
| 基因名 | TNFRSF9 |
|---|---|
| 基因全名 | Tumor necrosis factor receptor superfamily member 9 |
| 蛋白功能 | Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. |
| Tissue Specificity | Expressed on the surface of activated T-cells. |
| Uniprot ID | TNFRSF9: Q07011 |
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