产品名称 | RDH12 Retinol Dehydrogenase 12 Human Recombinant Protein |
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产品描述 | RDH12 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 303 amino acids (39-316) and having a molecular mass of 33.5kDa. RDH12 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | RDH12 Retinol Dehydrogenase 12 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ96NR8) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered colorless solution. |
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内容 | The RDH12 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 40% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | RDH12 |
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基因全名 | Retinol dehydrogenase 12 |
蛋白功能 | Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments. |
Tissue Specificity | Widely expressed, mostly in eye, kidney, brain, skeletal muscle and stomach. |
Uniprot ID | RDH12: Q96NR8 |
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