产品名称 | RBBP4 Retinoblastoma Binding Protein 4 Human Recombinant Protein |
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产品描述 | RBBP4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 449 amino acids (1-425 a.a) and having a molecular mass of 50.2kDa. RBBP4 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | RBBP4 Retinoblastoma Binding Protein 4 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ09028) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered colorless solution. |
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内容 | RBBP4 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM EDTA. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | RBBP4 |
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基因全名 | Histone-binding protein RBBP4 |
蛋白功能 | Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. |
Uniprot ID | RBBP4: Q09028 |
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