产品名称 | RAN, Member RAS Oncogene Family Human Recombinant Protein |
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产品描述 | RAN Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 236 amino acids (1-216 a.a.) and having a molecular mass of 26.5 kDa. The RAN is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
文献引用格式 | RAN, Member RAS Oncogene Family Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP62826) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile filtered colorless solution. |
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内容 | RAN Human solution containing 20mM Tris-HCl pH-8,1mM DTT & 10% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | RAN |
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基因全名 | GTP-binding nuclear protein Ran |
蛋白功能 | GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. |
Tissue Specificity | Expressed in a variety of tissues. |
Uniprot ID | RAN: P62826 |
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