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RALA V-ral Simian Leukemia Viral Oncogene Homolog A Human Recombinant Protein 1mg

价:
29660.40
价:
¥29660.40

号:PROTP11233

牌:BOSTER 博士德

账期 货到付款

EA (预计5-7工作日到货)

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周一至周五:9:00-18:00

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Product Brief

  • 产品概况

    产品名称 RALA V-ral Simian Leukemia Viral Oncogene Homolog A Human Recombinant Protein
    产品描述 RALA Human Recombinant fused with a 24 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 227 amino acids (1-203 a.a.) and having a molecular mass of 25.8kDa. The RALA is purified by proprietary chromatographic techniques.
    文献引用格式 RALA V-ral Simian Leukemia Viral Oncogene Homolog A Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP11233)
    应用范围 Cell Culture
    抗体来源 No

    产品详情

    产品形态 Sterile Filtered colorless solution.
    内容 The RALA solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 2mM DTT, 100mM NaCl and 0.1mM PMSF.
    *可以提供无载体抗体。
    储存条件 Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

    指标相关信息 (来源: Uniprot.org)

    小贴士:你可以利用tissue specificity信息来帮助设计阳性和阴性对照。对此有疑问请联系我们技术服务部门。
    基因名 RALA
    基因全名 Ras-related protein Ral-A
    蛋白功能 Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin- dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.
    Uniprot ID RALA: P11233

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