产品名称 | RAB1A, Member RAS Oncogene Family Recombinant Protein Human |
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产品描述 | RAB1A produced in E.Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids (1-205.a.a) and having a molecular mass of 24.8kDa. RAB1A is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | RAB1A, Member RAS Oncogene Family Recombinant Protein Human (Boster Biological Technology, Wuhan, China. Catalog #PROTP62820) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered clear solution. |
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内容 | The RAB1A protein solution (0.5mg/1ml) is formulated in 20 mM Tris-HCl buffer (pH8.0), 0.1M NaCl, 1mM DTT and 20% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | RAB1A |
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基因全名 | Ras-related protein Rab-1A |
蛋白功能 | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport. |
Uniprot ID | RAB1A: P62820 |
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