RAB17, Member RAS Oncogene Family Human Recombinant Protein 1mg

产品概况

产品名称	RAB17, Member RAS Oncogene Family Human Recombinant Protein
产品描述	RAB17 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (1-212) and having a molecular mass of 25.6 kDa. The RAB17 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
文献引用格式	RAB17, Member RAS Oncogene Family Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9H0T7)
应用范围	Cell Culture
抗体来源	No

产品名称

RAB17, Member RAS Oncogene Family Human Recombinant Protein

产品描述

RAB17 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (1-212) and having a molecular mass of 25.6 kDa.
The RAB17 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

文献引用格式

RAB17, Member RAS Oncogene Family Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9H0T7)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	RAB17 is supplied as a sterile filtered clear solution.
内容	RAB17 protein 0.5mg/ml is supplied in 20mM Tris-HCL, pH-8, 0.1M NaCl, 1mM DTT and 30% Glycerol. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

RAB17 is supplied as a sterile filtered clear solution.

内容

RAB17 protein 0.5mg/ml is supplied in 20mM Tris-HCL, pH-8, 0.1M NaCl, 1mM DTT and 30% Glycerol.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	RAB17
基因全名	Ras-related protein Rab-17
蛋白功能	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post- endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.
Tissue Specificity	Expressed in melanocytes (at protein level).
Uniprot ID	RAB17: Q9H0T7

基因名

RAB17

基因全名

Ras-related protein Rab-17

蛋白功能

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post- endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

Tissue Specificity

Expressed in melanocytes (at protein level).

Uniprot ID

RAB17: Q9H0T7

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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