QKI Human Recombinant Protein 10ug

产品概况

产品名称	QKI Human Recombinant Protein
产品描述	QKI Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 364 amino acids (1-341 a.a) and having a molecular mass of 40.1kDa. QKI is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
文献引用格式	QKI Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ96PU8)
应用范围	Cell Culture
抗体来源	No

产品名称

QKI Human Recombinant Protein

产品描述

QKI Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 364 amino acids (1-341 a.a) and having a molecular mass of 40.1kDa.
QKI is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

文献引用格式

QKI Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ96PU8)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterile Filtered clear solution.
内容	QKI protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM DTT. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterile Filtered clear solution.

内容

QKI protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM DTT.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	QKI
基因全名	Protein quaking
蛋白功能	RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)- UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
Tissue Specificity	Expressed in the frontal cortex of brain. Down-regulated in the brain of schizophrenic patients.
Uniprot ID	QKI: Q96PU8

基因名

QKI

基因全名

Protein quaking

蛋白功能

RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)- UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).

Tissue Specificity

Expressed in the frontal cortex of brain. Down-regulated in the brain of schizophrenic patients.

Uniprot ID

QKI: Q96PU8

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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