PTPN6 Protein Tyrosine Phosphatase Non Receptor Type-6 Human Recombinant Protein 1mg

产品概况

产品名称	PTPN6 Protein Tyrosine Phosphatase Non Receptor Type-6 Human Recombinant Protein
产品描述	PTPN6 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 300 amino acids and having a molecular mass of 34.3 kDa. The protein coding region of the catalytic domain of PTPN6 (amino acids 243-541). The catalytic domain of PTPN6 was overexpressed as insoluble protein aggregates (inclusion bodies). The recombinant PTPN6 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Additional amino acid(Met) is attached at N-terminus.
文献引用格式	PTPN6 Protein Tyrosine Phosphatase Non Receptor Type-6 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP29350)
应用范围	Cell Culture
抗体来源	No

产品名称

PTPN6 Protein Tyrosine Phosphatase Non Receptor Type-6 Human Recombinant Protein

产品描述

PTPN6 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 300 amino acids and having a molecular mass of 34.3 kDa. The protein coding region of the catalytic domain of PTPN6 (amino acids 243-541). The catalytic domain of PTPN6 was overexpressed as insoluble protein aggregates (inclusion bodies). The recombinant PTPN6 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Additional amino acid(Met) is attached at N-terminus.

文献引用格式

PTPN6 Protein Tyrosine Phosphatase Non Receptor Type-6 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP29350)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterile filtered colorless solution.
内容	The protein contains 25mM Tris-HCl, pH 7.5, 2mM b-mercaptoethanol, 1mM EDTA, 1mMDTT and 20% Glycerol. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterile filtered colorless solution.

内容

The protein contains 25mM Tris-HCl, pH 7.5, 2mM b-mercaptoethanol, 1mM EDTA, 1mMDTT and 20% Glycerol.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	PTPN6
基因全名	Tyrosine-protein phosphatase non-receptor type 6
蛋白功能	Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Tissue Specificity	Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.
Uniprot ID	PTPN6: P29350

基因名

PTPN6

基因全名

Tyrosine-protein phosphatase non-receptor type 6

蛋白功能

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

Tissue Specificity

Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.

Uniprot ID

PTPN6: P29350

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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