产品名称 | MIP-3b Macrophage Inflammatory Protein-3 Beta Human Recombinant Protein (CCL19) |
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产品描述 | Macrophage Inflammatory Protein-3 beta Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of 8.8kDa. The MIP-3b is purified by proprietary chromatographic techniques. |
文献引用格式 | MIP-3b Macrophage Inflammatory Protein-3 Beta Human Recombinant Protein (CCL19) (Boster Biological Technology, Wuhan, China. Catalog #PROTQ99731) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered White lyophilized (freeze-dried) powder. |
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内容 | Lyophilized without any additives. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | CCL19 |
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基因全名 | C-C motif chemokine 19 |
蛋白功能 | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
Uniprot ID | CCL19: Q99731 |
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