产品名称 | MIP-3b Macrophage Inflammatory protein-3 (CCL19) Human Recombinant Protein, T7 Tag |
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产品描述 | MIP3b Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 93 amino acids (22-98 a.a.) and having a molecular mass of 10.4kDa. MIP3b is fused to a 16 amino acid T7-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | MIP-3b Macrophage Inflammatory protein-3 (CCL19) Human Recombinant Protein, T7 Tag (Boster Biological Technology, Wuhan, China. Catalog #PROTO70460-1) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered clear solution. |
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内容 | MIP3b protein solution (0.5mg/ml) containing Phosphate Buffered Saline pH7.4 and 10% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | Ccl19 |
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基因全名 | C-C motif chemokine 19 |
蛋白功能 | Strongly chemotactic for naive (L-selectinhi) CD4 T- cells and for CD8 T-cells and weakly attractive for resting B- cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
Tissue Specificity | Highly expressed by dendritic cells in mesenteric and peripheral lymph nodes. Significant expression in spleen (T cell zone or periarteriolar lymphatic sheath) and Peyer patches. Low expression in thymus. |
Uniprot ID | Ccl19: O70460 |
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