产品名称 | MIP-1b Macrophage Inflammatory Protein-1 Beta Human Recombinant Protein (CCL4) |
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产品描述 | Macrophage Inflammatory Protein-1 beta Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 69 amino acids and having a molecular mass of 7620 Dalton. The CCL4 is purified by proprietary chromatographic techniques. |
文献引用格式 | MIP-1b Macrophage Inflammatory Protein-1 Beta Human Recombinant Protein (CCL4) (Boster Biological Technology, Wuhan, China. Catalog #PROTP13236) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered White lyophilized (freeze-dried) powder. |
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内容 | Lyophilized from a concentrated (1mg/ml) solution in water containing no additives. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | CCL4 |
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基因全名 | C-C motif chemokine 4 |
蛋白功能 | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
Uniprot ID | CCL4: P13236 |
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