MICA Human, MHC class I chain-related gene A, Human Recombinant ProteinHis Tag 1mg

产品概况

产品名称	MICA Human, MHC class I chain-related gene A, Human Recombinant ProteinHis Tag
产品描述	MICA Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 283 amino acids (24-297aa) andhaving a molecular mass of 32.7kDa. MICA is fused to an 8 amino acid His-tag at C-terminus& purified by proprietary chromatographic techniques.
文献引用格式	MICA Human, MHC class I chain-related gene A, Human Recombinant ProteinHis Tag (Boster Biological Technology, Wuhan, China. Catalog #PROTQ29983-1)
应用范围	Cell Culture
抗体来源	No

产品名称

MICA Human, MHC class I chain-related gene A, Human Recombinant ProteinHis Tag

产品描述

MICA Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 283 amino acids (24-297aa) andhaving a molecular mass of 32.7kDa.
MICA is fused to an 8 amino acid His-tag at C-terminus& purified by proprietary chromatographic techniques.

文献引用格式

MICA Human, MHC class I chain-related gene A, Human Recombinant ProteinHis Tag (Boster Biological Technology, Wuhan, China. Catalog #PROTQ29983-1)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterile Filtered clear solution.
内容	MICA protein solution (0.25mg/ml) containing Phosphate bufferedsaline (pH7.4), 10% glycerol and 1mM DTT. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterile Filtered clear solution.

内容

MICA protein solution (0.25mg/ml) containing Phosphate bufferedsaline (pH7.4), 10% glycerol and 1mM DTT.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	MICA
基因全名	MHC class I polypeptide-related sequence A
蛋白功能	Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T- cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Tissue Specificity	Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T-cells.
Uniprot ID	MICA: Q29983

基因名

MICA

基因全名

MHC class I polypeptide-related sequence A

蛋白功能

Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T- cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

Tissue Specificity

Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T-cells.

Uniprot ID

MICA: Q29983

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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