产品名称 | MIA2 Melanoma Inhibitory Activity 2 Human Recombinant Protein |
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产品描述 | MIA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain consisting of 101 amino having a total molecular mass of 11.5 kDa. The MIA2 is purified by proprietary chromatographic techniques. |
文献引用格式 | MIA2 Melanoma Inhibitory Activity 2 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ96PC5) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered White lyophilized (freeze-dried) powder. |
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内容 | The MIA2 protein was lyophilized from a concentrated (1mg/ml) solution containing 20mM Phosphate buffer pH=7.4 and 150mM NaCl. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | MIA2 |
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基因全名 | Melanoma inhibitory activity protein 2 |
蛋白功能 | Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Isoform 1 plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (PubMed:27138255). Thereby, may play a role in cholesterol and triglyceride homoestasis (By similarity). |
Tissue Specificity | Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis (PubMed:12586826). Isoform 1 is specifically expressed in lung, testis, small intestine, colon, pancreas, kidney, liver and prostate (PubMed:27138255). |
Uniprot ID | MIA2: Q96PC5 |
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