产品名称 | MGMT O-6-Methylguanine-DNA Methyltransferase Human Recombinant Protein |
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产品描述 | MGMT Human Recombinant fused to a 20 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 227 amino acids (1-207) and having a molecular mass of 23.8 kDa. The MGMT is purified by proprietary chromatographic techniques. |
文献引用格式 | MGMT O-6-Methylguanine-DNA Methyltransferase Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP16455) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered clear colorless solution. |
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内容 | The MGMT solution contains 20mM Tris-HCl pH-7.5, 1mM DTT and 10% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | MGMT |
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基因全名 | Methylated-DNA--protein-cysteine methyltransferase |
蛋白功能 | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
Uniprot ID | MGMT: P16455 |
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