产品名称 | MEMO1 Mediator of Cell Motility 1 Human Recombinant Protein |
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产品描述 | MEMO1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 322 amino acids (1-297 a.a) and having a molecular mass of 36.4kDa. MEMO1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | MEMO1 Mediator of Cell Motility 1 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9Y316) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered colorless solution. |
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内容 | MEMO1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer, pH8.0, 50% glycerol, 5mM DTT, 300mM NaCl and 2mM EDTA. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | MEMO1 |
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基因全名 | Protein MEMO1 |
蛋白功能 | May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. |
Uniprot ID | MEMO1: Q9Y316 |
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