LINGO1 Leucine Rich Repeat And Ig Domain Containing 1 Human Recombinant Protein 20ug

产品概况

产品名称	LINGO1 Leucine Rich Repeat And Ig Domain Containing 1 Human Recombinant Protein
产品描述	LINGO1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 133 amino acids (241-337 a.a) and having a molecular mass of 15.1kDa. LINGO1 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
文献引用格式	LINGO1 Leucine Rich Repeat And Ig Domain Containing 1 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ96FE5)
应用范围	Cell Culture
抗体来源	No

产品名称

LINGO1 Leucine Rich Repeat And Ig Domain Containing 1 Human Recombinant Protein

产品描述

LINGO1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 133 amino acids (241-337 a.a) and having a molecular mass of 15.1kDa. LINGO1 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

文献引用格式

LINGO1 Leucine Rich Repeat And Ig Domain Containing 1 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ96FE5)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterile Filtered colorless solution.
内容	LINGO1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterile Filtered colorless solution.

内容

LINGO1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	LINGO1
基因全名	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
蛋白功能	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).
Tissue Specificity	Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients.
Uniprot ID	LINGO1: Q96FE5

基因名

LINGO1

基因全名

Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

蛋白功能

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Tissue Specificity

Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients.

Uniprot ID

LINGO1: Q96FE5

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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